How to Apply Your Butrans Patch

Butrans patches are available in different strengths and patch sizes. Make sure you have the right strength patch that has been prescribed for you, and review the steps below before applying your Butrans patch.

The application instructions provided here are intended as a guide, and do not include all of the steps you must follow when using Butrans.

Please review the Instructions for Use you received with your Butrans prescription before starting your treatment with Butrans.

If you have any questions, talk to your healthcare professional or pharmacist.

Choose an application site

  • Butrans should be applied to the left or right upper outer arm, upper chest, upper back, or the side of the chest for a total of 8 different application sites in all
patch locations
  • It is important to change the skin site where you apply your Butrans patch every week (exactly 7 days), making sure that at least 3 weeks (21 days) pass before you re-use the same site
  • If you are wearing a patch, remember to remove it before applying a new one
  • Do not use soap, alcohol, lotions, oils, or other products to remove any leftover adhesive from a patch, because this may cause more medicine to pass through the skin
  • Do not apply more than 1 patch at the same time unless your healthcare professional tells you to do so
  • If you are using 2 patches as prescribed, remember to apply them at the same site right next to each other. Always apply and remove the 2 patches together at the same time

Prepare the skin

  • Butrans should be applied to hairless or nearly hairless skin. If needed, you can clip the hair at the site, but do not shave the area
  • The skin should be free of cuts and irritation (rashes, swelling, redness, or other skin problems)
  • Use only water to clean the site, and allow the skin to dry completely before applying the patch (do NOT use soaps, alcohol, oils, lotions, or abrasive devices)
no shaving icon

Remove the patch from its pouch

  • Each patch is sealed in its own protective pouch
  • Do not use a patch if the seal on its protective pouch is broken or if the patch is cut, damaged, or changed in any way
  • Cut the pouch open along the dotted line and remove the patch
  • Do not remove the patch from the pouch until you are ready to use it
cut the patch

Remove the liner from the patch

  • Hold the patch with its protective liner facing you
  • Gently bend the patch along the faint line and peel back the larger portion of the liner, which covers the sticky surface of the patch
  • Do not touch the sticky side of the patch with your fingers
remove the linear

Place the patch on your skin

  • Using the smaller part of the protective liner as a handle, apply the sticky side of the patch to one of the 8 body locations described in step 1
Patch the skin

Remove the protective liner

  • While holding the sticky side down, gently fold back the smaller portion of the patch
  • Grasp an edge of the remaining protective liner and slowly peel it off
remove the liner

Press the patch firmly into place

  • Press down on the entire patch for about 15 seconds with the palm of your hand (do not rub)
  • Make sure the patch firmly sticks to the skin and go over the edges with your finger to ensure good contact around the patch
press on chest

Wash Up

  • Always wash your hands after applying or handling a Butrans patch
sink icon
See how to dispose of your Butrans patch.